The Energy Dissipation to Defect Evolution (EDDE) EFRC aims to develop a fundamental understanding of how the energy of radiation is dissipated, and ultimately to control defect dynamics and microstructural evolution in structural alloys. Specifically, we seek to understand and quantify the mechanisms of energy dissipation through electronic, vibrational and magnetic excitation, their impact on atomic processes that control defect production and recombination under irradiation, and how their dissipation mechanisms are influenced by alloy complexity.